Sexually Transmitted Diseases

Sexually Transmitted Diseases

DiseaseEffectDoseAdverse Reactions
SyphilisSkin rash Ulcers Mucocutaneous lesions lymphadenopathyPenicillin G       Benzamine penicillinMild rash, nausea, vomiting, overactive reflexes, muscle spasm. Stomach upset, diarrhea Skin rash, bruising, sore throat, muscle weakness, bloody diarrhea, swollen glands, joint pain, fast heartbeat, blurred vision, headache, and dizziness.
Chlamydial infection,Cervicitis in women Urethritis in men Oropharyngeal and rectal infections Extra genital infections Ectopic pregnancy Infertility  azithromycin 1 g administered orally as a single dose doxycycline 100 mg administered twice a day orally for seven daysNausea, abdominal pain, stomach upset, vomiting, and affect heart rhythm Difficulty swallowing, diarrhea, drug rash, headache, esophageal ulcer, facial redness, esophagitis, nausea
HIV AIDSSore throat Fatigue Flu-like symptoms Fever, weight loss, Recurrent infections Night sweats      Nucleoside Reverse Transcriptase Inhibitors : abacavir,   didanosine (ddl),                           lamivudine (3TC)                            stavudine (d4T),                          zalcitabine (ddC),   zidovudine (ZDV)          Sleep problems, general ill feeling, strange dreams, Nausea and vomiting, fever, chills, ear pain, and rash. Nausea, diarrhea, abdominal pain, headache, vomiting, fever and rash. Malaise, headache, tiredness, diarrhea, abdominal pain, coughing Nausea, headache, vomiting, loss of appetite, rash, difficulty falling asleep. Liver failure, inflammation of the pancreas, metabolic disturbance, and peripheral neuropathy.   Liver problems, lactic acidosis, blood disorders, and myopathy.
GonorrheaPain or burning sensation when urinating Slightly green, creamy, or watery vaginal discharge Heavier spotting or periods Sore throat Sharp pain in lower abdomen, vagina, or testicles Pain during sex Fever  Azithromycin 1g oral single dose Ceftriaxone, 1g intravenous muscle injection every 24 hours   Cefotaxime, 1g intravenous injection every 8 hoursAbdominal pain, stomach upset, loose stool, vomit, and nausea Diarrhea, rash, upset stomach, dizziness, headache, nausea, blood clot. Swelling or pain on the tongue, a lump at the location on injection. Fever, vomiting, nausea, rash, abdominal pain, irritation, pain, inflammation, or hard lump at the injection site.
ChlamydiaPain during sex Bleeding between periods Swollen or tender testicles Burning sensation or pain when urinating Abnormal vaginal discharge Pain, bleeding, or discharge around the  anus Milky discharge or pus from the penis  Azithromycin   Erythromycin   doxycyclineVomiting, diarrhea, abdominal pain, nausea, Abdominal pain, anorexia, vomiting, diarrhea Diarrhea, headache, esophagitis, drug rash, difficulty swallowing, hives, facial redness, and esophageal ulcer
Pelvic inflammatory diseasePain during sex and during urination, pain in the lower abdomen, lower back, pelvis, or pelvis, fatigue, chills, fever, menstrual and leg cramps, nausea, or vomiting.Cefotetan           doxycyclineLoss of appetite, redness, swelling, soreness, or pain at the site of injection, stomach pain, vomiting or nausea, diarrhea, vaginal discharge or itching, and headache Diarrhea, esophagitis, difficulty swallowing, facial redness, drug rash, esophageal ulcer, hives
Genital HerpesTingling or itching around the anal or genital area Cracked, red, or raw areas around the genitals without itching, pain, or tingling Small blisters that break o cause pain Pain on sores during urination  Acyclovir         Famciclovir         valacyclovirDiarrhea, agitation, dizziness, hair loss, stomach or intestinal irritation, headache, hair loss, muscle pain Stomach pain, diarrhea, headache, tired feeling, gas, nausea, sleepiness, dizziness, numbness or tingly feeling, skin rash or itching Headache, stomach pain, nausea, dizziness
Human Papillomavirus (HPV)Common warts  on hands or fingers Female genital warts Flat warts Male genital warts Plantar warts itching        Podofilox           Imiquimod         Podophyllin     interferon       Trichloroacetic acid(TCA)  Insomnia, pain during sex, unpleasant odor, cysts, vomiting or nausea, scarring, the foreskin does not retract, skin ulceration, blood in the urine Headache, tingling, pain, or swelling in the affected area, bumps, scabs, or blisters, scaling, dryness, or flaking of skin Stinging, severe burning, itching, easy bleeding or bruising, redness, swelling Chills, swelling or interactions on injection site, fever, vomiting, trouble sleeping, chills Swelling of area medicine is applied, burning, skin tenderness


Cruickshank, H. (2019).Everything you need to know about sexually transmitted diseases (STDs). Healthline. Retrieved from

Healthy Children (2015) Medications for sexually transmitted infections. Healthy Children Organization. Retrieved from

Penyakit, B.K., Malaysia, K.K.(2015). MYCDCGP – Malaysian Guidelines In The Treatment of Sexually Transmitted Infection. Malaysia: BKPKKM

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